Properties
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- tableti saghech i
What is it?
Calci-D3 Nicomed Dosage form, dosage Chewable tablets with mint flavor Pharmacotherapeutic group Gastrointestinal tract and metabolism. Mineral supplements. Calcium preparations. Calcium preparations in combination with other drugs. Indications for use Prevention and treatment of calcium and vitamin D deficiency; additional therapy for osteoporosis in patients at risk of calcium and vitamin D deficiency. List of data required before use Contraindications Do not take Calci-D3 Nicomed if you are allergic to calcium, vitamin D or any other component of this medicine, have severe kidney problems, hypercalcemia and/or hypercalciuria, kidney stones, hypervitaminosis D, fructose intolerance, glucose-galactose malabsorption. Precautions for use Before taking Calci-D3 Nicomed, consult your doctor or pharmacist • if you are undergoing long-term treatment, especially if you are also taking diuretics (medicines for blood pressure and fluid retention) or cardiac glycosides (medicines for heart disease); • if you have signs of impaired kidney function or a strong tendency to form kidney stones; • if you have sarcoidosis (an immune system disorder that can increase vitamin D levels in the body); • if you have osteoporosis and are immobile; • if you are taking other vitamin D-containing preparations. Additional doses of calcium and vitamin D should be controlled by a doctor. Interactions with other medicines Thiazide diuretics can reduce calcium excretion in urine. Due to the risk of increased calcium levels in the blood, regular monitoring of serum calcium levels is necessary when Calci-D3 Nicomed and thiazide diuretics are taken together. Cardiac glycosides can increase their toxic effects in cases of hypercalcemia. When Calci-D3 Nicomed and cardiac glycosides are taken together, serum calcium levels and electrocardiogram (ECG) readings should be monitored. Calcium carbonate can affect the absorption of tetracycline antibiotics. Therefore, tetracyclines should be taken at least two hours before or four to six hours after taking Calci-D3 Nicomed. The effect of quinolone antibiotics may be reduced when taken with calcium. Quinolone antibiotics should be taken two hours before or six hours after taking Calci-D3 Nicomed. Bisphosphonate-containing preparations (anti-osteoporosis drugs) should be taken at least one hour before taking Calci-D3 Nicomed. The effectiveness of levothyroxine may be reduced when taken with calcium due to decreased absorption of levothyroxine. At least four hours should pass between taking Calci-D3 Nicomed and levothyroxine. Calcium salts can reduce the absorption of iron, zinc, and strontium ranelate. As a result, iron, zinc, or strontium ranelate preparations should be taken at least two hours before or after taking Calci-D3 Nicomed. Treatment with orlistat may potentially impair the absorption of fat-soluble vitamins (e.g., vitamin D3). Special warnings During long-term treatment, attention should be paid to serum calcium levels and kidney function should be monitored by measuring serum creatinine levels. Monitoring is particularly important in elderly patients with concomitant treatment with cardiac glycosides and diuretics, and in patients with a strong tendency to form kidney stones. In cases of signs of hypercalcemia or impaired kidney function, the dosage should be reduced or treatment discontinued. Calcium carbonate with cholecalciferol should be prescribed with caution in patients with signs of hypercalcemia or impaired kidney function; calcium and phosphate levels in blood and urine must be monitored. The risk of soft tissue calcification should be considered. When taking other sources of vitamin D and/or calcium-containing medicinal products or food supplements, there is a risk of hypercalcemia and milk-alkali syndrome with subsequent impaired kidney function. In such patients, serum calcium levels and kidney function should be monitored. Calci-D3 Nicomed should be prescribed with caution in patients with sarcoidosis due to the risk of increased conversion of vitamin D to its active form. In such patients, calcium levels in serum and urine should be monitored. Calci-D3 Nicomed should be prescribed with caution to immobilized patients with osteoporosis due to the risk of developing hypercalcemia. The preparation Calci-D3 Nicomed contains sucrose, which may be harmful to teeth. The tablets also contain isomalt (E953). Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption, and sucrose-isomaltase deficiency should not take this preparation. One tablet of Calci-D3 Nicomed contains 23 mg of sodium, which means it contains almost no sodium. No dose adjustment is required in liver failure. Use during pregnancy and lactation Pregnancy Women can use Calci-D3 Nicomed during pregnancy in case of calcium and vitamin D deficiency. The daily dose during pregnancy should not exceed 2500 mg of calcium and 4000 IU of vitamin D. However, pregnant women should not take excessive doses of calcium and vitamin D, as persistent hypercalcemia has an adverse effect on the developing fetus. Vitamin D has no teratogenic effect at therapeutic doses. Lactation Calci-D3 Nicomed can be taken during lactation. Calcium and vitamin D3 pass into breast milk. This should be taken into account when prescribing additional vitamin D to the infant. Features of the effect of the preparation on the ability to drive vehicles or operate potentially dangerous machinery Calci-D3 Nicomed does not affect the ability to drive vehicles and operate machinery. Recommendations for use Dosage regimen Calcium and vitamin D deficiency: Adults: 1 tablet 1-3 times a day; Children: 1 tablet 1-2 times a day; Additional therapy for osteoporosis: Adults and elderly: 1 tablet 2-3 times a day. Method and rule of administration The tablet can be chewed or dissolved. Measures to be taken in case of overdose If you have taken more Calci-D3 Nicomed than you should, consult your doctor immediately. Measures to be taken in case of omission of one or more doses of the medicine Do not take a double dose to make up for a missed dose. Recommendations for consulting a healthcare professional For clarification on how to take the medicine, always take the preparation in full accordance with the instructions in this leaflet and the recommendations of your doctor or pharmacist. If in doubt, consult your doctor or pharmacist. Description of undesirable reactions that occur with standard use and measures to be taken in this case Like all medicines, Calci-D3 Nicomed can cause undesirable reactions in some patients. Infrequently, excess calcium in the blood (hypercalcemia) and urine (hypercalciuria) may occur with high doses. Rarely, constipation, dyspepsia, flatulence, vomiting, abdominal pain, and diarrhea. Very rarely, itching, rash, and urticaria. Milk-alkali syndrome (frequent urge to urinate; prolonged headache; prolonged loss of appetite; vomiting or nausea; fatigue or weakness; hypercalcemia, alkalosis, and kidney failure). Usually occurs with overdose. Unknown (cannot be assessed based on available data) Hypersensitivity reactions, such as angioedema or laryngeal edema. If you experience the following symptoms: swelling of the face, tongue, lips or throat, consult a doctor immediately! In patients with kidney failure, there is a risk of increased phosphate levels in the blood (hyperphosphatemia), kidney stone formation (nephrolithiasis), and increased calcium content in the kidneys (nephrocalcinosis). If adverse drug reactions occur, consult a healthcare professional, pharmacist, or report directly to the database of adverse drug reactions (effects), including reports of drug ineffectiveness. Additional information Composition of the medicinal product One tablet contains active ingredients: Calcium carbonate 1250 mg (equivalent to 500 mg elemental calcium), Cholecalciferol 5.5 mcg (200 IU vitamin D3) in the form of cholecalciferol concentrate* 2.20 mg * Cholecalciferol concentrate contains, including a 10% excess: Cholecalciferol 0.0055 mg, DL-α-tocopherol 0.0220 mg, Medium-chain triglycerides 0.0660 mg, Modified corn starch 1.61 mg, Sucrose 0.385 mg, Sodium ascorbate 0.0880 mg, Silicon dioxide 0.0264 mg. Excipients: Xylitol, mint flavor granules (containing isomalt, mint flavoring substance, mono- and diglycerides of fatty acids), povidone, magnesium stearate, sucralose. Description of appearance, smell, taste Round, biconvex, uncoated, white tablets with a mint flavor. May have small dots and irregular edges. Dosage form and packaging 30 or 120 tablets in a high-density polyethylene bottle with a screw cap. 1 bottle with instructions for medical use in Kazakh and Russian languages is placed in a cardboard box. Shelf life 30 months. Do not use after the expiry date! Storage conditions Store in a tightly closed bottle at a temperature not exceeding 25°C, in a dry place. Keep out of reach of children! Dispensing category: Pharmaceutical product group - III, available without a prescription See also: Calcium+D3 Orange - Calcium+D3 30 chewable tablets with orange flavor