Lan-30 Lansoprazole Capsule 30mg #30

International Name - lansoprazole Clinical-Pharmacological Group: Gastroenterology, Hepatology → Anti-ulcer agents Pharmacological Properties It is a remedy for gastric ulcer disease. It blocks the final stage of hydrochloric acid formation. In the parietal cells of the stomach, it is converted into an active form – sulfonamide. It reduces basal and stimulated (food, pentagastrin, insulin) secretion and secretion volume. The rate of inhibition of hydrochloric acid secretion depends on the dose. It has a gastroprotective effect: strengthening mucosal oxygenation and bicarbonate secretion. It suppresses the growth of Helicobacter pylori, reduces blood circulation in the antral part of the stomach, and suppresses the motor-evacuatory function of the stomach. Indications Non-ulcer dyspepsia, gastric and duodenal ulcer disease, erosive-ulcerative esophagitis, reflux esophagitis, Zollinger-Ellison syndrome, Helicobacter pylori infection (combined treatment). Dosage and Administration Orally in the morning. Non-ulcer dyspepsia: 15-30 mg/day. Duodenal ulcer: 30 mg/day for 2-4 weeks. Gastric ulcer: 30-60 mg/day for 4-8 weeks, reflux esophagitis: 30 mg/day for 4 weeks, Zollinger-Ellison syndrome: dose is selected individually, which ensures a basal acidity level of 10 mmol/h. Helicobacter pylori infection: 30 mg twice a day (combined treatment). Side Effects Gastrointestinal tract: diarrhea, rarely increased or decreased appetite, nausea, stomach pain, constipation. Nervous system: headache, drowsiness. Skin: rarely rash, angioedema, sometimes interstitial nephritis, liver dysfunction, leukopenia, thrombocytopenia. Contraindications Hypersensitivity to the components of the preparation, malignant neoplasms of the gastrointestinal tract, pregnancy (especially the first trimester), childhood.