Myleni Vaginal Capsule #6

International Nonproprietary Name - comb. drug Clinical-pharmacological group: Obstetrics, gynecology → Antiprotozoal, antimicrobial and antifungal agents for local use Composition and dosage form One soft vaginal capsule contains: Metronidazole 400 mg Miconazole nitrate 100 mg Centella Asiatica 15 mg Polymyxin sulfate 5 mg Neomycin sulfate 45 mg Excipients: Mineral oil, white petrolatum. Pharmacological properties Maylen has antimycotic, antibacterial, and antiprotozoal action. It also exhibits a trophic effect that promotes the regeneration of vaginal epithelium. Microbiology: Maylen acts on microorganisms such as Trichomonas, Gardnerella vaginalis, Campylobacter-like bacteria, Gram-negative and Gram-positive microorganisms, and fungi, especially Candida genus. Pharmacokinetics Absorption after vaginal administration is negligible, and therefore low plasma levels are observed. Indications Maylen is used for the treatment of vaginal infections. Local treatment of vulvovaginal mycoses, trichomonal vaginitis, and nonspecific vaginitis when infection by microorganisms sensitive to neomycin and polymyxin is suspected. Dosage and administration Adults: 1 capsule is inserted deep into the vagina, at night before sleep, for 6-12 days. Side effects Side effects are local: burning or irritation, itching. Contraindications Hypersensitivity to any component of the preparation. Although absorption is negligible, the use of the preparation during the first three months of pregnancy is not recommended. Warning: Alcohol consumption is not allowed during treatment. The use of this preparation does not protect against sexually transmitted diseases. Special instructions Use with caution in patients with CNS diseases, hematological diseases, or severe liver failure. Pregnancy: Do not use during the first three months of pregnancy; thereafter, the doctor assesses the benefits and risks of using the preparation. Lactating mothers: Although absorption is very weak, the decision on its use should be made by a doctor. Overdose Due to the method of use and weak absorption, the risk of overdose is unlikely. Interactions with other drugs Concomitant use of oral anticoagulants (warfarin or dicoumarol) may increase prothrombin time and the tendency to bleed. Alcohol consumption during treatment may cause vomiting, sweating, hypotension.