Properties
What is it?
International Name - Papaverinum hydrochloridi Pharmacological Group: Preparations affecting the tone and motility of smooth muscles Composition: Each 1 ml of the preparation contains 20mg of Papaverine hydrochloride. Excipients: EDTA, methionine, water for injection. Indications: Functional disorders and pain caused by spasms of the smooth muscles of blood vessels, abdominal cavity, and bronchi. Used for spasms of cerebral and coronary blood vessels and hypertensive crises; also for spastic colitis, cholecystitis, spasms of the urinary tract, and renal colic. Dosage and Administration: Subcutaneous, intramuscular, and intravenous injections. Intravenous injections should be administered slowly under medical supervision! Single dose 0.04g (2ml of 2% solution). Maximum single dose for adults is 0.1g, daily dose is 0.3g. For children, depending on age, 0.005-0.06g 2 times a day. Contraindications: Hypotension, atrioventricular block, age under 1 year or elderly, glaucoma, individual hypersensitivity to the preparation. Side Effects: Atrioventricular block, ventricular extrasystole, hypotension, elevated transaminase levels in blood, drowsiness, sweating. Pregnancy and Lactation: Safety and efficacy have not been established. Interaction with Other Drugs: Combination with cardiac glycosides causes a marked enhancement of myocardial contractility. Precautions and Special Instructions: The preparation is prescribed in small doses and with caution to elderly patients, patients with liver and kidney failure, craniocerebral trauma, pronounced vascular hypotension, and patients with impaired conduction in the heart vessels. Work with potentially hazardous mechanisms and driving require special caution. Overdose: Intravenous administration of high doses of the preparation may cause arrhythmias or atrioventricular blocks. Treatment is symptomatic.
