Properties
What is it?
International Nonproprietary Name - Benzalkonium chloride+Aloe Trade Name: ClearZal. International Nonproprietary Name: Benzalkonium chloride. Dosage Form: Solution for external use, with glass applicator in a cardboard box. Composition: Benzalkonium chloride, Aloe. Description: Odorless, white liquid. With glass applicator. Pharmacotherapeutic Group: Preparation with antibacterial, antiviral, and antifungal action. Pharmacological Properties: A topical antifungal agent with antiviral and antibacterial action. At a concentration of 0.1%, ClearZal Bac-i has fungicidal action against dermatophytes, molds, and some dimorphic fungi. ClearZal Bac-i disrupts sterol synthesis in fungi at early stages. This leads to ergosterol deficiency and intracellular accumulation of squalene, causing fungal cell death. Benzalkonium chloride is a broad-spectrum antibiotic that destroys local bacteria and viruses by 99.9%. It has a well-defined bactericidal, virucidal, and antifungal effect. It is active against both Gram(+) and Gram(-) strains. ClearZal Bac-i does not affect the human cytochrome P450 enzyme system and therefore does not affect the metabolism of hormones or other medicinal products. ClearZal Bac-i also contains aloe, which has a softening effect that promotes the regeneration of damaged skin and rapid nail growth. Pharmacokinetics: It has a local effect, does not enter systemic circulation. Indications: Onychomycosis. Contraindications: Hypersensitivity to the components of the preparation. Age up to 6 years. Side Effects: In rare cases, redness and itching may occur. If these symptoms appear, the use of the preparation should be discontinued. Method of Use and Dosage: Apply twice daily around the entire nail and under the free edge of the nail to the site of infection. Before applying the preparation, it is necessary to clean and dry the affected area. Duration of treatment is 2-8 weeks. Precautions: The preparation should not come into contact with the mouth, nose, or eyes. Dosage Form: 0.1% solution for external use, 30 ml/l with glass applicator in a cardboard box. Storage Conditions: Store in a place inaccessible to children, not exceeding 25 C. Dispensing Conditions: Available without a prescription. Manufacturer: DiaDerm. USA.