Properties
What is it?
International Nonproprietary Name - Calcium carbonate+magnesium carbonate Pharmacological group: Anti-ulcer agents Indications for use Symptoms associated with increased stomach acidity, heartburn, belching, periodic stomach pain, indigestion, dyspepsia (feeling of fullness or heaviness in the epigastric region, nausea). Dosage and administration Adults and children over 12 years of age: Single dose - 1-2 tablets, which can be chewed or dissolved in the mouth until completely absorbed. Use when symptoms appear or one hour after meals and before bedtime. The daily dose of 8g calcium carbonate, equivalent to 11 tablets, must not be exceeded. As with other antacids, if symptoms persist for 14 days after administration, diagnostic measures are recommended to rule out a more serious condition. Side effects Immune system: Very rarely allergic reactions - rash, urticaria, Quincke's edema, and anaphylaxis. Gastrointestinal tract: Nausea, vomiting, indigestion, diarrhea. Metabolism and nutrition: In patients with impaired kidney function, the use of the drug can cause reactions associated with hypermagnesemia, hypercalcemia, and alkalosis, which can provoke gastrointestinal symptoms (nausea, vomiting, constipation) and muscle weakness. Musculoskeletal and connective tissue: Muscle weakness. Nervous system: Loss of taste, headache. Kidneys and urinary tract: Azotemia. Side effects associated with milk-alkali syndrome: Asthenia and calcinosis. Contraindications Nephrocalcinosis, severe renal failure, hypercalcemia, hypercalciuria, hypophosphatemia, hereditary diseases associated with fructose intolerance, glucose-galactose malabsorption, or sucrose-isomaltase deficiency; hypersensitivity to the ingredients of the drug, myasthenia gravis, intestinal obstruction. Overdose Prolonged use of the drug in high doses, especially in patients with impaired kidney function, can lead to renal failure, hypermagnesemia, hypercalcemia, and alkalosis, which can provoke gastrointestinal symptoms (nausea, vomiting, constipation) and muscle weakness. In such cases, it is necessary to discontinue the drug and drink sufficient fluids. In severe cases of overdose (e.g., milk-alkali syndrome), medical consultation is required, as additional measures to restore water balance may be necessary.
