
Properties
- Form
- tableti
- Dosage mg
- 300
- Pack
- 30
What is it?
International Name - Allopurinol Composition: Allopurinol tablets contain 100 mg, 150 mg, 200 mg, or 300 mg of allopurinol as the active substance. Excipients: lactose, sodium starch glycolate, povidone, and magnesium stearate. Pharmacotherapeutic group: Anti-gout agent. Indications: Gout, treatment of cancer and treatment with diuretics, kidney stones, certain skin diseases, and certain enzyme disorders such as Lesch-Nyhan syndrome. Dosage and administration: Tablets should be swallowed with water after meals. The appropriate dose for the patient will be determined by the treating physician. Adults: The initial dose of allopurinol is 100 mg per day. The treating physician will then increase the dose by 100 mg at weekly intervals to a maintenance dose suitable for the patient, usually 200-600 mg per day. In severe cases, the dose may be 700-900 mg per day. If the patient is taking allopurinol concurrently with cancer treatment, allopurinol should be started 2-3 days before cancer treatment with initial doses of 200 mg three times a day. At the beginning of treatment, the treating physician may advise the patient to take colchicine or a non-steroidal anti-inflammatory drug to prevent attacks. If the patient has liver or kidney disease, or is taking certain medications such as mercaptopurine or azathioprine, the treating physician may prescribe a lower dose. During hemodialysis, the dose is 300-400 mg after each dialysis. Elderly: The minimum maintenance dose will be selected by the doctor. Children under 15 years of age (for the treatment of cancer or enzyme disorders): The usual daily dose is 10-20 mg/kg body weight per day, with a maximum of 400 mg per day. Side effects: Skin reactions such as rash, hives, itching, peeling skin, burning or blistering, scratching or redness of the skin, sensitivity, purple spots on the skin. These may be followed by more severe allergic reactions. If the patient experiences any of the following, they should stop taking the tablets and consult their doctor immediately: fever and chills, headache, muscle pain, and general malaise, sores in the mouth, throat, nose, genitals, red and swollen eyes, widespread blisters or peeling skin, severe hypersensitivity reactions including fever, skin rash, joint pain, blood and liver function test abnormalities, sudden wheezing, difficulty breathing, swelling of the mouth, throat, tongue, or face, sometimes collapse, swelling of the armpits, groin, or neck glands. Nausea or vomiting, changes in liver function. Diarrhea, muscle pain, back pain, sore throat, chills, liver diseases including yellowing of the skin or whites of the eyes, abdominal pain, loss of appetite, problems with urination, tingling, numbness, muscle weakness. Chest pain, high blood pressure, slow pulse, blood in urine or bloody vomiting, fever, depression. Headache, dizziness, drowsiness, diabetes, vision changes or cataracts, taste disturbances, changes in bowel function or oily stools, feeling of loss of balance or numbness, inability to move muscles or loss of consciousness, bruising, subcutaneous bleeding, fatigue, pale skin, frequent infections. Purulent infection of the hair follicle accompanied by pain, high cholesterol levels in the blood. Fluid retention causing swelling, hair loss or discoloration, mouth ulcers, male fertility disorders, erectile dysfunction, and enlargement of the mammary glands.
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