Properties
What is it?
Composition and Dosage Form Gargle - Oral Solution: 200 ml bottle Benzydamine Hydrochloride . . . . 300 mg Chlorhexidine Gluconate . . . . 240 mg Excipients: Saccharin, Ethanol, and Peppermint Essence. Oral Spray: 30 ml bottle Benzydamine Hydrochloride . . . . 0.15% Chlorhexidine Gluconate . . . . 0.12% Excipients: Saccharin, Ethanol, and Peppermint Essence. Each spray volume is 0.13 ml, containing 0.156 mg of Chlorhexidine Gluconate and 0.195 mg of Benzydamine Hydrochloride. Clinical-Pharmacological Group Non-steroidal anti-inflammatory drug for topical use in oral diseases. Pharmacological Properties Benzydamine is a structurally different anti-inflammatory and analgesic agent from steroids. Benzydamine has a different pharmacological profile from other non-steroidal anti-inflammatory drugs. Indications - Adjunctive therapy for antibacterial treatment of sore throat, pharyngitis, laryngitis, and tonsillitis; - For mucositis, inflammation of the oral mucosa caused by chemotherapy, radiotherapy, and other physical causes (e.g., tracheal intubation); - Aphthous ulcers, glossitis; - For relief of oropharyngeal and throat pain after periodontal procedures, as well as oral, dental, and jaw surgeries; - Treatment and prevention of gingivitis; - Treatment of oral infections and their complications; - Treatment of inflammation of the oral mucosa (stomatitis); - Prevention of plaque and tartar on teeth; - Periodontal diseases, periodontosis caused by physical exertion; - As adjunctive treatment after conservative dental therapy and tooth extraction; - For oral hygiene. Dosage Regimen Gargle Usually, Benet Plus Gargle is used undiluted. After rinsing, the solution should be expectorated. Adults: The single dose of Benet Plus Gargle is 15 ml (measuring cap filled to the last mark). It is rinsed for 30 seconds at 1.5-3 hour intervals throughout the day. Chlorhexidine in Benet Plus Gargle reduces the formation of tartar and gingivitis during treatment. Therefore, if Benet Plus Gargle is used as an oral hygiene procedure, the preparation should be held in the mouth for at least 1 minute, and after use, the solution should be expectorated. To minimize staining caused by chlorhexidine, it is recommended to brush teeth before using Benet Plus. Children (6-12 years): 5-15 ml of Benet Plus solution is rinsed in the mouth for 30 seconds at 1.5-3 hour intervals. The duration of treatment should not exceed 7 days. The preparation can be diluted with water if burning or numbness occurs. Spray Adults: The spray should be applied directly to the inflamed area of the throat/oropharynx or ulcer. The usual dose is 4-8 sprays at a time. If necessary, the preparation can be used every 1.5-3 hours, with a maximum of 32 sprays per day. Chlorhexidine in Benet Plus Spray reduces the formation of tartar and gingivitis during treatment. Therefore, if Benet Plus Spray is used as an oral hygiene procedure, the preparation should be held in the mouth for at least 1 minute, and after use, the solution should be expectorated. To minimize staining caused by chlorhexidine, it is recommended to brush teeth before using Benet Plus. Pregnancy and Lactation Pregnancy (Category B): There are no controlled study data on the use of chlorhexidine and benzydamine during pregnancy and lactation. This preparation should be used during pregnancy only if necessary. Lactation: It is not known whether chlorhexidine and benzydamine are excreted in breast milk, so the preparation should be used with caution during lactation. Storage Conditions