Properties
What is it?
Composition Active substance: Simethicone (dimethicone activated with silicon dioxide) 66.66 mg/ml. Excipients: Sodium saccharin, methylparahydroxybenzoate, propylparahydroxybenzoate, sodium carmellose, citric acid monohydrate, raspberry flavoring, purified water. Pharmacological properties Antifoaming agent. Simethicone (activated dimethicone) is a combination of methylated linear siloxane polymers, stabilized by trimethylsiloxy groups of silicon dioxide. By reducing the surface tension at the phase interface, it hinders the formation of gas bubbles and promotes their disintegration in the chyme and gastrointestinal mucus. The released gases can be absorbed by the intestinal wall and eliminated through peristalsis. This prevents the formation of large gas-mucus conglomerates that cause painful bloating. During sonography and radiography, it prevents image defects; it promotes better lavage of the colonic mucosa with contrast agents, preventing the rupture of the contrast film. Simethicone is not absorbed in the gastrointestinal tract after oral administration and is excreted unchanged in the feces. Consequences of chemical inertness: It does not affect microorganisms and enzymes in the gastrointestinal tract. It does not reduce food absorption and does not alter the reaction or volume of gastric juice. Indications • Excessive gas formation and gas accumulation in the gastrointestinal tract (painful colic, feeling of fullness in the abdomen, aerophagia, dyspepsia, meteorism, including in the postoperative period, Remheld's syndrome). • Preparation of abdominal and pelvic organs for diagnostic studies (radiography, sonography, gastroscopy, and duodenoscopy – prevention of foam formation). • As an additive to contrast agent suspensions for double contrast imaging. • As an antifoaming agent in acute poisoning with detergents. Dosage and administration For oral administration. Shake the preparation before use until a homogeneous emulsion is obtained. To accurately measure the dose, hold the bottle vertically during drops. For excessive gas formation and gas accumulation in the gastrointestinal tract. Bobotik is usually administered three times a day after meals and before bedtime. • From the 28th day of life to 2 years: 8 drops (20 mg simethicone) 4 times a day. • From 2 to 6 years: 14 drops (35 mg simethicone) 4 times a day. • For children over 6 years of age and adults: 16 drops (40 mg simethicone) 4 times a day. For easier administration, especially in young children, it can be initially mixed with a small amount of boiled cooled water, baby food, or non-carbonated liquid. Treatment continues until the gas disappears. Preparation for diagnostic procedures Radiographic examination of the gastrointestinal tract: 1 day before the examination, in the morning and evening, the following dose is required: • From the 28th day of life to 2 years: 10 drops (25 mg simethicone) 2 times a day. • From 2 to 6 years: 16 drops (40 mg simethicone) 2 times a day. • For children over 6 years of age and adults: 20 drops (50 mg simethicone) 2 times a day. Ultrasonographic examination of the gastrointestinal tract: One day before the examination, in the morning and evening (depending on age), take the same amount of the preparation as for preparation for radiographic examination. 3 hours before the examination, the dose should be repeated. Side effects There is no data on the side effects of the preparation. In case of any undesirable (unusual) effects not indicated in the package insert, inform your doctor. Packaging In a 30 ml dark glass bottle with a polyethylene dropper and a screw-on polyethylene cap. The bottle, equipped with a label and instructions for use, is placed in an individual cardboard package. Contraindications • Hypersensitivity to simethicone and/or other components of the preparation. • Intestinal obstruction. • Obstructive diseases of the gastrointestinal tract. Pregnancy and lactation Currently, there is no data indicating that simethicone has teratogenic or embryotoxic effects. The preparation can be used during pregnancy and lactation as prescribed by a doctor. Special instructions Bobotik does not contain sugar, therefore it can be used by patients with diabetes mellitus and impaired digestion. It is not recommended to consume carbonated beverages while taking Bobotik. Administration of the preparation may significantly alter the results of some diagnostic tests, such as the guaiac resin test. Effect on driving and operating machinery. It has no effect. Overdose The preparation is chemically inert and is not absorbed from the gastrointestinal tract. To date, there is no data on Bobotik overdose. Interaction with other drugs According to some data, simethicone may cause impaired absorption of oral anticoagulants. Storage conditions and shelf life Shelf life: 3 years. The preparation must not be used after the expiry date indicated on the packaging. Storage conditions: Store in the original packaging at 15-25°C. Keep out of reach of children. Dispensing from pharmacy: Without prescription