Properties
What is it?
Cistibacti® Oral dispersible powder in sachet 2g 15 sachets per pack Cistibacti® is a food supplement with Cysti-Complex®. The complex contains D-mannose, bearberry and cranberry extracts, beta-glucan, palmitoylethanolamide (PEA). Ingredients: Cysti-Complex® (D-mannose, bearberry Arctostaphylos uva-ursi L. leaf tit. dry extr. 20% arbutin, cranberry Vaccinium macrocarpum Aiton fruit tit. dry extr. 40% proanthocyanidins, beta-glucan, PEA (palmitoylethanolamide)). Anti-caking agent: silicon dioxide; sweeteners: erythritol, sucralose; flavorings. Content of active ingredients per 1 sachet: Cysti-Complex® - 533 mg D-mannose - 200 mg Bearberry Arctostaphylos uva-ursi L. - 167 mg leaf dry extr. tit. 20% arbutin - 33.5 mg Cranberry Vaccinium macrocarpum Aiton fruit dry extr. tit. 40% - 133 mg proanthocyanidins - 53 mg Beta-glucan - 33 mg PEA (palmitoylethanolamide) - 60 mg Product purpose and mechanism: Cistibacti® is a food supplement intended for the prevention of urinary tract infections and maintaining the normal function of the urinary system. The Cysti-Complex® contained in it creates a protective barrier in the urinary system to prevent the development of new infections or their recurrence. This product is a natural origin, antibiotic-sparing strategy aimed at reducing the risk of developing antibiotic resistance. D-mannose It is a simple sugar of natural origin. After oral administration, most of it is excreted unchanged in the urine. It mimics the receptors required for uropathogens to attach to the urothelial cells of the host organism. D-mannose competitively binds to bacterial surface ligands, reducing the number of bacteria attached to the mucous membrane and shifting the balance of interaction between the host and pathogens in favor of the host. Cranberry fruit extract It is a natural bacteriostatic and anti-inflammatory agent. It inhibits the adhesion of uropathogens to urothelial cells through several mechanisms. In particular, proanthocyanidins contained in cranberry extract inhibit the adhesion of uropathogenic E. coli mediated by P-fimbriae, while fructose inhibits adhesion mediated by type-1 fimbriae. Type-1 fimbriae of uropathogenic E. coli are responsible for infection persistence, enhancement of inflammatory response, and ascending spread of bacteria by disrupting the contractility of the urinary tract. P-fimbriae ensure the adhesion of uropathogens to the surface of the upper urinary tract and kidney cells; they are responsible for the development of complicated infections. Arbutin, the main antimicrobial component of bearberry leaf extract, modifies the bacterial cell wall and significantly reduces pathogen adhesion to the urothelium. It stimulates diuresis (without affecting sodium and potassium excretion) and exhibits anti-inflammatory action. Beta-glucans They are polysaccharides that form the cell wall of some bacteria and fungi. They bind to specific receptors on the cell surface and enhance the body's immune defense by stimulating the activity of the complement system, macrophages, and natural killer cells. Palmitoylethanolamide (PEA) It is an endogenous substance of the endocannabinoid family, produced in tissues in response to inflammatory stimuli. It performs a protective function and promotes cell regeneration. Areas of the central nervous system responsible for pain control are rich in cannabinoid receptors. Their stimulation activates pain reduction mechanisms. PEA exhibits an analgesic effect by selectively acting on CB2 receptors. It also has an anti-inflammatory effect at the peripheral level by inhibiting the degranulation of mast cells. Dosage and administration: Take 1-2 sachets per day. The contents of the sachet are taken directly, without water. If desired, it can be taken dissolved in water. Warnings: - Keep out of reach of children under 3 years of age. - Do not exceed the recommended daily dose. - Food supplements are not intended to replace a varied and balanced diet or a healthy lifestyle. Storage conditions: - Store in a cool, dry place, away from heat sources. - The expiry date refers to the product stored correctly in an unopened package. Do not use after the expiry date indicated on the packaging. Manufacturer: "Promofarma", San Marino. Distributor: LLC "30 Georgia", M. Kostava 75g, Tbilisi, Georgia