Cingal syringe 88mg/18mg 4ml

Cingal Syringe 88mg/18mg 4ml Description Cingal is the world's first and only combination product that combines: - Cross-linked hyaluronic acid (HA), which provides joint lubrication and load cushioning - Triamcinolone hexacetonide (TH) — a potent corticosteroid that rapidly reduces inflammation Cingal is unique because it combines rapid and long-lasting mechanisms of action simultaneously – this rare combination in a single injection provides both immediate and months-long pain relief. It is ideal for patients who want quick relief, but also long-term improvement and to delay surgery. Formula and Composition Cingal is a sterile, clear, single-use injectable gel containing: - 22 mg/ml cross-linked hyaluronic acid (HA) - 4.5 mg/ml triamcinolone hexacetonide (TH) HA provides joint lubrication and mechanical protection, while TH helps with rapid and long-lasting control of inflammation. The injection is administered once into the knee joint. Composition (in 4ml) - Hyaluronic acid – 88 mg - Triamcinolone hexacetonide – 18 mg - Phosphate buffered solution, polysorbate, sorbitol, and water for injection Packaging Form 5 ml sterile glass syringe containing 4 ml of injectable gel. Clinical Indicators - Rapid pain relief effect in the first week - Long-lasting effect – up to 6 months - 92% of patients showed a positive response - Can delay knee replacement surgery for up to 3 years Indications Cingal is used to reduce pain, stiffness, and difficulty with movement caused by knee osteoarthritis. Mechanism of Action - HA improves the properties of synovial fluid - TH rapidly reduces the inflammatory process - Together, they provide both rapid and long-lasting results Dosage and Administration - Single 4 ml injection - The injection must be administered by a doctor, following sterile technique - Use immediately after opening Contraindications Cingal is not recommended for patients who: - Have hypersensitivity to hyaluronic acid or corticosteroids - Have a skin infection at the injection site - Have an existing joint infection - Rarely – active thyroid, pulmonary, or other chronic infectious diseases that require individual assessment by a doctor Note: These conditions do not lead to automatic restrictions and require only a doctor's consultation. Side Effects - Minor pain, swelling, or redness at the injection site - Mostly short-lived and self-resolving - Rarely – joint irritation requiring medical evaluation Precautions - Use only as directed by a doctor - Do not use if the packaging is open or damaged - Do not inject into blood vessels - Do not use in children, pregnant, or breastfeeding women (safety not fully established) Storage At a temperature of 2–25°C. Do not freeze. Use immediately after opening. Shelf Life 3 years from the date of manufacture. The expiry date is indicated on the packaging.