Iodinol - Iodine 100ml

Trade name: Iodinol. International Nonproprietary Name: Iodine. Dosage form: Solution for external use. Description: Dark blue liquid with a characteristic odor, foams when shaken. Traces of foam formation are permissible on the unfilled part of the vial. Composition: One vial contains: Active substance - Iodine - 100 mg; Excipients - Potassium iodide, Polyvinyl alcohol, Purified water. Pharmacotherapeutic group: Antiseptic and disinfectant agents. Pharmacological action Pharmacodynamics Iodinol (Iodopolyvinyl alcohol, Iodopolyvinyl alcohol) is a product of the molecular (crystalline) combination of iodine with polyvinyl alcohol. Iodinol is less toxic. It has antiseptic properties. When applied to large skin surfaces, iodine has a resorptive effect: it actively affects metabolism, enhances dissimilation processes, participates in thyroxine synthesis, and has a proteolytic effect; polyvinyl alcohol is a high-molecular compound, the content of which in Iodinol slows down the release of iodine and prolongs its interaction with body tissues; it also reduces the irritating effect of iodine on tissues. Iodine has a bactericidal effect on both gram-positive and gram-negative flora, as well as pathogenic fungi and yeasts, acting most actively on streptococcal flora and E. coli. Staphylococci are more resistant to the action of Iodinol, however, with prolonged use, their elimination is observed in 80% of cases. Pseudomonas aeruginosa is resistant to the use of Iodinol. Pharmacokinetics Upon contact with skin or mucous membranes, it is converted to iodides by 30%, and the rest is converted to active iodine. Partially absorbed. The absorbed portion reaches tissues and organs, is selectively absorbed by the thyroid gland. It is excreted mainly by the kidneys, intestines, sweat, and mammary glands. Indications for use Chronic tonsillitis, chronic purulent otitis, chronic atrophic rhinitis (ozena), purulent wounds, trophic and varicose ulcers of the skin, thermal and chemical burns of I-II degree. Contraindications Hypersensitivity to the components of the preparation, thyrotoxicosis, pregnancy and lactation, thyroid diseases (nodular colloid goiter, endemic goiter, and Hashimoto's thyroiditis), dermatitis herpetiformis Duhring, simultaneous therapy with iodine, age up to 6 years (no experience of use). Precautions Use with caution in patients under 18 years of age. Do not allow the preparation to come into contact with the eyes. If this happens, the eyes should be rinsed with plenty of water or a 1% sodium thiosulfate solution. In individuals with renal and hepatic insufficiency, as well as in individuals over 70 years of age, Iodinol should be used with extreme caution under the control of thyroid function (once every 2 weeks). Effect on laboratory parameters. Against the background of Iodinol treatment, false results may be obtained when determining the levels of thyroid hormones and protein-bound iodine in blood plasma. Effect on the ability to drive vehicles and operate machinery. Currently, there is no data indicating that Iodinol affects the ability to drive vehicles and operate machinery. Pregnancy and lactation Pregnancy: The amount of iodine that can be absorbed with the use of this medicinal product is a priori low. However, iodine-based preparations should not be prescribed during pregnancy, especially in the third trimester, due to the risk of fetal hypothyroidism and neonatal goiter. Therefore, as a precautionary measure, the use of this preparation during pregnancy should be avoided. Lactation: Iodine is excreted in breast milk, so the use of the preparation during breastfeeding should be avoided. Method of administration and dosage In chronic tonsillitis, the lacunae of the tonsils and supratonsillar space are irrigated with the medicinal product. Only 4-5 irrigations with an interval of 2-3 days. Single dose is 50 ml. In purulent otitis: daily instillation of 5-8 drops of Iodinol (for mesotympanitis) or irrigation of the attic (for epitimpanitis). The course of treatment is 2-4 weeks. In the treatment of atrophic rhinitis (ozena), after preliminary softening and removal of crusts, the nasal cavity and pharynx are sprayed with Iodinol 2-3 times a week for 2-3 months. For trophic and varicose ulcers, the skin should first be washed with warm water and soap, and the area around the ulcer should be treated with zinc ointment. A three-layer gauze dressing soaked in Iodinol should be applied to the surface of the ulcer. Dressings are applied 1-2 times a day (depending on the discoloration of the dressing), and the gauze on the surface of the ulcer should not be removed, but re-soaked with Iodinol. After 4-7 days of general or local baths, the indicated treatment continues. In purulent wounds and infected burns, a loose gauze dressing soaked in the medicinal product is used, which should be changed periodically as needed. Wound cavities should be rinsed with Iodinol, after which it is introduced into the cavity on a tampon. If there is no positive effect within 2 to 7 days, consult a doctor. Overdose Symptoms For external use: signs of iodism - skin rash, rhinitis, lacrimation, hypersalivation, rhinorrhea, bronchorrhea, swelling of mucous membranes. Treatment: Withdrawal of the preparation, symptomatic therapy. Symptoms in case of accidental or intentional oral intake of Iodinol: signs of iodism - metallic taste in the mouth, increased salivation, increased sweating, burning or pain in the throat and mouth, eye irritation and swelling of the eyelids, nasopharynx, larynx, difficulty breathing (pulmonary edema), skin reactions, gastrointestinal disorders (nausea, vomiting, intestinal spasms and diarrhea). Tachycardia, metabolic acidosis, hypernatremia, and renal failure may develop. Treatment: Gastric lavage first with a 1% sodium thiosulfate solution, then with water; symptomatic therapy. In case of overdose symptoms, as well as other symptoms not described here, it is necessary to stop taking the preparation and consult a doctor immediately. Interaction with other medicinal products The medicinal product is incompatible with disinfectants containing mercury compounds, pharmaceutically incompatible with essential oils, ammonia solutions, antiseptics from the group of alkalis and oxidizers. It alters the effectiveness of medicinal products that affect thyroid function. Iodinol can be combined with physiotherapy and, if necessary, with antibiotics. Absorption of iodine from iodine can affect thyroid function. Alkaline or acidic environment, the presence of fat, pus, blood weakens the antiseptic effect. Side effects Allergic reactions (skin itching). In individuals with idiosyncrasy to iodine, signs of iodism may occur in the form of skin rash or rhinitis, itching, swelling and irritation of mucous membranes (lacrimation, hypersalivation, rhinorrhea, bronchorrhea), which does not require special measures or discontinuation of treatment. From the thyroid gland: goiter, hypothyroidism or hyperthyroidism. Metabolic acidosis, hypernatremia, and impaired kidney function (when applied to large areas of mucous membranes or in individuals with extensive burns). In case of occurrence of the listed side reactions, as well as reactions not indicated in the instructions, you must consult a doctor. Storage conditions Protected from light, at a temperature not exceeding 250C. Do not freeze. Keep out of reach of children. Shelf life 3 years. Do not use the medicinal product after the expiry date. Conditions of dispensing from pharmacies Pharmaceutical product group III, dispensed without a prescription. Information about the manufacturer Open Joint Stock Company "Borisov Plant of Medical Preparations", Republic of Belarus, Minsk region. Borisov, Chapaev str. # 64, Tel/Fax +375 (177) 735612, 731156.