Properties
- Form
- tableti
- Dosage mg
- 150
- Pack
- 28
What is it?
Active substance: hydrochlorothiazide, irbesartanEsantil Plus's combination of active ingredients has an additional antihypertensive effect, lowering blood pressure more effectively than either component alone.Contraindications:Esantil-Plus is contraindicated in patients with hypersensitivity to any component of this product. Due to the hydrochlorothiazide component, this medication is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs.Pregnancy and lactation:Pregnancy categories C (first trimester) and D (second and third trimesters)It is not known whether irbesartan is excreted in human milk, however, irbesartan and some of its metabolites are secreted in the milk of lactating rats at low concentrations. Due to the potential for adverse effects in the infant, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.Dosage and method of administration:The recommended starting dose of Esantil-Plus is 150 mg once daily. For patients requiring further reduction in blood pressure, titration up to 300 mg once daily is necessary.A lower starting dose of irbesartan (75 mg) is recommended in patients with intravascular volume depletion (e.g., patients receiving potent diuretics or on hemodialysis).Storage conditions:Store at room temperature up to 25C in its original packaging. Keep out of reach of children.