Properties
What is it?
International Nonproprietary Name (Active Substance): melatonin, pyridoxine Clinical-Pharmacological Group: Biologically Active Supplements 1 Tablet Composition: Melatonin - 3 mg Vitamin B6 - 5 mg Description: Round, biconvex, film-coated tablets of white or off-white to yellowish hue, with a dividing score on one side. Indications: Enhances sleep duration and quality Is a potent antioxidant Positively affects the cardiovascular system Strengthens the immune system Ensures complete rest and recovery Pharmacokinetics: When taken orally, it is rapidly and completely absorbed, easily crosses the histohematic barrier, including the blood-brain barrier. It has a partially short elimination period. Dosage and Administration: For oral administration. Adults: 1 tablet, children: 1/2 tablet once daily, 30-40 minutes before bedtime. After administration, it is necessary to avoid light. As an adaptogen when changing time zones: 1 tablet 30-40 minutes before bedtime, 1 day before flight and for the next 2-5 days. The maximum daily dose is 2 tablets per day. Side Effects: Allergic reactions to the components of the preparation are possible. In the first days of use, very rarely, swelling may occur. Headache, vomiting, nausea, diarrhea, morning drowsiness. Contraindications: Hypersensitivity, severe renal impairment, pregnancy and lactation. Special Instructions: During treatment, it is necessary to avoid driving vehicles and engaging in potentially hazardous activities that require increased concentration and rapid psychomotor reactions. Women planning pregnancy should be informed about the weak contraceptive effect of the preparation. Direct exposure to bright light should be avoided. Overdose: In case of accidental overdose: gastric lavage, symptomatic therapy. Intensification of side effects. Interactions with Other Drugs: Potentiates the effects of central nervous system depressants and beta-blockers. Simultaneous use with hormonal preparations is not recommended. Incompatible with MAO inhibitors, glucocorticosteroids, and cyclosporines. Storage Conditions and Shelf Life: Store the preparation in a place inaccessible to children, protected from light, at a temperature of 10-30°C.