Properties
What is it?
International Nonproprietary Name - diclofenac Clinical-pharmacological group: Anti-inflammatory agents → Non-steroidal anti-inflammatory agents → Non-steroidal anti-inflammatory agents for systemic use Description Clear, colorless or pale yellow solution, practically free of mechanical particles. Composition 3 ml solution (1 ampoule) contains: Active substance: Sodium diclofenac 75 mg. Excipients: Anhydrous alcohol, propylene glycol, sodium bisulfite, sodium hydroxide, water for injection. Dosage form Solution for injection Drug classification code Non-steroidal anti-inflammatory drug. Indications Diseases requiring rapid anti-inflammatory and/or analgesic effect: • Inflammatory rheumatic diseases; (Rheumatoid arthritis, seronegative spondyloarthritis, juvenile arthritis and arthritis of other etiology;) • Degenerative rheumatism of the musculoskeletal system (arthrosis, spondylosis); • Microcrystalline arthritis (gouty arthritis, pseudogouty arthritis); • Non-articular rheumatism (periarthritis, bursitis, myositis, tendinitis, synovitis;) • Other inflammatory diseases of the musculoskeletal system accompanied by pain syndrome. As an analgesic, Naklofen is used for soft tissue injuries, in the postpartum period in the absence of lactation, in primary and secondary dysmenorrhea, in dentistry, after surgical interventions, as well as for renal or biliary colic. Method of administration and dosage For severe pain - 75 mg (3 ml) once or twice daily intramuscularly. Treatment should be continued with other forms of the drug (enteric-coated tablets, sustained-release tablets, suppositories) as soon as possible. In case of renal colic, if necessary, repeated intramuscular administration of 75 mg Naklofen may be performed after 30 minutes. This dosage form is not intended for children. It is not recommended to mix the drug in the same syringe. Contraindications Hypersensitivity to diclofenac or any component of the preparation, salicylates or other non-steroidal anti-inflammatory drugs, manifested by bronchial asthma, urticaria or rhinitis; Peptic ulcer disease of the stomach and duodenum, gastrointestinal bleeding. Severe heart failure Overdose Symptoms: Vomiting, nausea, epigastric pain, dizziness, tinnitus and irritation, possible hematemesis, melena, impaired consciousness, respiratory distress, convulsions and renal failure. Treatment: Symptomatic. There is no specific antidote. Forced diuresis, hemodialysis are less effective.