Properties
What is it?
International Nonproprietary Name - Sodium chloride Clinical-pharmacological group: Anesthesiology, Resuscitation, Transfusiology → Rehydration and detoxification agents for parenteral use → Saline solutions Composition and dosage form 1 ampoule contains: Sodium chloride _ 90 mg, Water for injection – up to 10 ml. Indications The preparation is used for significant loss of extracellular fluid (toxic dyspepsia, cholera, diarrhea, vomiting, extensive burns with severe exudation, etc.), hypochloremia and hyponatremia accompanied by dehydration, intestinal obstruction, intoxication, as well as for wound irrigation, rinsing of mucous membranes of the eye and nasal cavity, dilution and dissolution of various medicinal substances, and moistening of dressings. Dosage and administration The preparation is administered intravenously (dropwise) and subcutaneously, and is also used rectally and externally. Before administration, the solution is warmed to 36-38°C. The dose of the preparation is determined by the amount of fluid lost by the body. On average, 5 ml to 2 L is administered per day. In cases of intoxication and significant fluid loss, up to 3 L of the preparation can be administered per day. The infusion rate is 540 ml/h. If necessary, the infusion rate is increased. When administering large doses of 0.9% sodium chloride solution for a prolonged period, it is necessary to monitor the electrolyte content in plasma and urine. When administered subcutaneously, the volume of the solution is 5 ml or more, depending on indications. Rectally, 75-100 ml is administered per administration. Side effects Acidosis, hyperhydration, hypokalemia. Contraindications Hypernatremia, acidosis, hyperchloremia, hypokalemia, extracellular hyperhydration; circulatory disorders that pose a risk of brain and lung edema; cerebral edema, pulmonary edema, acute left ventricular failure, simultaneous administration of large doses of glucocorticoids. Pregnancy and lactation No data available. Special instructions The preparation should be used with particular caution in chronic renal failure (oliguria, anuria), chronic decompensated heart failure. The preparation may freeze, provided the hermetic sealing of the ampoules is maintained. Overdose No data available. Interaction with other drugs When mixing with other medicinal products, visual control of compatibility is required. Storage conditions and shelf life Store in a place protected from light, at a temperature not exceeding 25°C. Keep out of reach of children. Shelf life is 2 years. The preparation is not allowed to be used after the expiry date indicated on the packaging. Dispensing from pharmacies Pharmaceutical product group II (Dispensing regime: by prescription).