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Ozempic® Solution for Injection 1mg/0.74ml 4 Doses Pen Composition: Active substance - semaglutide What is Ozempic® and what is it used for? Ozempic® is a glucagon-like peptide 1 (GLP-1) receptor agonist containing the active ingredient semaglutide. Indication: To improve blood sugar (glucose levels) in adults with type 2 diabetes, along with diet and exercise. To reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease (1). To reduce the risk of sustained decline in eGFR, end-stage renal disease, and cardiovascular death in adults with type 2 diabetes and chronic kidney disease. Ozempic® is not intended for people with type 1 diabetes, where the body does not produce insulin; Ozempic® is not recommended for children and adolescents under 18 years of age, as safety and efficacy have not yet been established in these age groups. How to use Ozempic®: Follow your doctor's instructions exactly when taking this medication. The starting dose is 0.25 mg once weekly for four weeks. After four weeks, your doctor will increase the dose to 0.5 mg once weekly. Your doctor may increase the dose to 1 mg or 2 mg weekly. Do not change your dose without your doctor's advice. How to use: Each dose contains 1 mg of semaglutide in 0.74 ml of solution. Ozempic® is administered as a subcutaneous injection. The best injection sites are the front of your thigh, abdomen, or the upper part of your arm. You can inject at any time of day, regardless of meal times. Do not stop taking this medication without consulting your doctor. If you miss a dose of Ozempic® If you miss an injection and it has been 5 days or less since you used Ozempic®, use it as soon as you remember. Then, take your next dose as usual on your scheduled day. If it has been more than 5 days since you used Ozempic®, skip the missed dose. Then, take your next dose as usual on your scheduled day. Do not use a double dose to make up for a missed dose. Storage: Before opening: Store in the refrigerator (at 2°C to 8°C). Do not freeze. During use: The pen can be stored for up to 6 weeks if kept at a temperature below 30°C or in the refrigerator (2°C to 8°C). Precautions: The most common side effects observed in ≥5% of patients treated with Ozempic® are nausea, vomiting, diarrhea, abdominal pain, and constipation. Before using Ozempic®, tell your healthcare provider if you have any other medical conditions, including if: you have had or have problems with your pancreas or kidneys. you have a history of diabetic retinopathy. you are pregnant or breastfeeding or plan to become pregnant or breastfeed. You should stop using Ozempic® 2 months before becoming pregnant. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and other diabetes medicines, including insulin or sulfonylureas. What are the possible side effects of Ozempic®? Ozempic® may cause serious side effects, including: Inflammation of the pancreas (pancreatitis). Stop using Ozempic® and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that does not go away, with or without vomiting. Tell your healthcare provider if you have changes in your vision while being treated with Ozempic®. If you use Ozempic® with another medicine that can cause low blood sugar, such as sulfonylurea derivatives or insulin. Signs and symptoms of low blood sugar may include: dizziness or lightheadedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shaking, weakness, headache, fast heartbeat, and feeling jittery. Kidney problems (kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting can cause a loss of fluids (dehydration), which may worsen kidney problems. It is important for you to drink fluids to reduce your chance of dehydration. Serious allergic reactions. Stop using Ozempic® and get medical help right away if you have symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; nausea or dizziness; or a very fast heartbeat.