Properties
- Form
- tableti
- Dosage mg
- 4.07
- Pack
- 30
What is it?
AMPECOR film-coated tablets Active substances: Amlodipine 5mg or 10mg (in the form of 6.935mg and 13.87mg amlodipine besylate, respectively) Indapamide 1.25mg, Perindopril 3.395mg (in the form of 4.07mg perindopril erbumine). Excipients: DC calcium carbonate, croscarmellose sodium, pregelatinized starch, microcrystalline cellulose (PH 112), colloidal silicon dioxide, magnesium stearate, hypromellose 2910, 6 cps, titanium dioxide, polyethylene glycol 6000, glycerin. Pharmacotherapeutic group Cardiovascular system drugs. Renin-angiotensin system agents. ACE inhibitors in combination with other drugs. Other ACE inhibitors. Perindopril in combination with amlodipine and indapamide. Indications As replacement therapy in patients with essential arterial hypertension, already controlled with a combination of perindopril/indapamide and amlodipine in the same doses. Dosage and administration AMPECOR is taken orally, one tablet once a day. The dose of the drug is selected after preliminary titration of the doses of its individual components. It is advisable to take the tablets in the morning, before meals. Additional data related to special patient groups Patients with renal insufficiency The drug is contraindicated in patients with severe renal insufficiency (CC less than 30 ml/min). Patients with moderate renal insufficiency (CC 30-60 ml/min) AMPECOR Forte doses 5 mg/2.5 mg/8.14 mg and 10 mg/2.5 mg/8.14 mg are contraindicated. Treatment should be initiated by selecting monocomponent doses. Constant medical supervision includes regular monitoring of plasma creatinine and potassium concentrations. Concomitant use of perindopril with aliskiren is contraindicated in patients with impaired renal function (GFR less than 60 ml/min/1.73 m2). Patients with hepatic insufficiency The drug is contraindicated in patients with severe hepatic insufficiency. In case of mild and moderate hepatic insufficiency, dose selection should be done with caution, as there are no clear recommendations for amlodipine dosing for this group of patients. Pediatric patients Currently, there is no data on the safe and effective use of the drug in children and adolescents. Elderly patients In elderly patients, perindoprilat excretion is slowed down. Treatment should be carried out taking into account renal function. Storage conditions: Store at a temperature not exceeding 25C, in the original packaging and out of reach of children