Properties
What is it?
International Nonproprietary Name - Arginin (Arginine aspartate) Composition: Active substance: 5 ml of solution contains 1g of L-arginine aspartate (L-arginine - 0.57 g, aspartic acid - 0.43 g); Excipients: Sorbitol (E 420), Sodium saccharin (E 954), Methylparahydroxybenzoate (E 218), Propylparahydroxybenzoate (E 216), Food flavoring "Caramel", Purified water. Dosage form. Solution for oral use. Pharmacotherapeutic group. Other cardiological preparations. Amino acids. ATC code C01E. Clinical characteristics. Indications. In complex therapy for ischemic heart disease, atherosclerosis of the heart and cerebral vessels, arterial hypertension, atherosclerosis of peripheral vessels, diabetic angiopathy, conditions after acute myocardial infarction and acute cerebrovascular disorders, cardiomyopathy, chronic heart failure, hypercholesterolemia, chronic obstructive pulmonary diseases, interstitial pneumonia, idiopathic pulmonary hypertension, chronic postembolic pulmonary hypertension, acute and chronic hepatitis of various etiologies, liver failure, hepatic encephalopathy caused by hyperammonemia, hypoxic and asthenic conditions, and reduced function of the thymus gland for immunocorrection. Contraindications. Hypersensitivity, severe renal impairment, pediatric age (up to 18 years). Method of administration and dosage. For internal use, during meals. For adults with ischemic heart disease, atherosclerosis of the heart and cerebral vessels, peripheral vessels, diabetic angiopathy: 5 ml (1 measuring spoon - 1 g of the preparation) 3-8 times a day. For hypercholesterolemia, conditions after acute myocardial infarction and acute cerebrovascular disorders: 5 ml 3-6 times a day. For chronic obstructive pulmonary diseases, interstitial pneumonia, idiopathic pulmonary hypertension, chronic postembolic pulmonary hypertension: 5 ml 3-6 times a day. For acute and chronic hepatitis of various etiologies, liver failure, hepatic encephalopathy caused by hyperammonemia: 5 ml 3-6 times a day. For hypoxic and asthenic conditions, immunocorrection with reduced thymus function: 5 ml 4-8 times a day. Maximum daily dose - 8-15 days; the course is repeated if necessary. Side effects. Rarely - mild discomfort in the stomach and intestines, nausea immediately after taking the preparation, which disappear on their own. Allergic reactions are possible. Overdose. Symptoms: hypersensitivity reactions, hypoglycemic conditions. Treatment. In case of the indicated events, it is necessary to discontinue the intake of the preparation. Gastric lavage is indicated, there is no antidote, therapy is symptomatic. Use during pregnancy or breastfeeding. The preparation crosses the placenta, so its use during pregnancy is possible only when the expected benefit to the mother outweighs the potential risk to the fetus. There are no data on the use of the preparation during breastfeeding. Children. There is no data on the use of the preparation in children under 18 years of age. Special precautions for use. Use with caution in case of electrolyte imbalance, kidney diseases. When taking the preparation, it is necessary to maintain a balanced sleep and rest regimen, abstain from alcohol, nicotine, and psychostimulants. If asthenia symptoms increase while taking the preparation, treatment should be discontinued. Ability to influence reaction rate when driving vehicles or operating other machinery. Does not affect.