Properties
What is it?
TREVITON B injectable solution 100mg-100mg-1mg Thiamine hydrochloride; Pyridoxine hydrochloride; Cyanocobalamin Composition: The injectable solution contains: Thiamine hydrochloride 100mg; Pyridoxine hydrochloride 100mg; Cyanocobalamin 1.0mg and excipients: Benzyl alcohol, Lidocaine hydrochloride, Sodium hydroxide (for pH adjustment), Sodium hexametaphosphate, Potassium ferricyanide-III, Water for injection. Indications: Systemic neurological disorders caused by deficiency of vitamins B1, B6, and B12, which cannot be corrected by dietary adjustments. Contraindications: Hypersensitivity to the active substances or any of the excipients. This medication is contraindicated in patients with severe conduction disorders and congestive heart failure. Pregnancy and lactation: Daily intake of up to 25mg of vitamin B6 is safe during pregnancy and lactation. Since this preparation is packaged in 100mg-2ml vials, its use during pregnancy and lactation is not recommended. Children and elderly patients: TREVITON B is not used in children under 12 years of age due to benzyl alcohol and high vitamin doses. No special precautions are necessary for elderly patients. Dosage and administration: Dosage: In case of severe or acute pain, treatment starts with 1 injection (2ml) per day. After the acute phase of the process and in case of secondary disease, 1 injection is given 2-3 times a week. Weekly monitoring of treatment is recommended. Transition to oral treatment should occur as soon as possible. Method of administration: Deep intramuscular injection. Possible side effects: Benzyl alcohol can, in rare cases, cause anaphylactoid reactions. Unknown frequency: Hypersensitivity reactions (e.g., exanthema, dyspnea, shock, angioedema); dizziness, somnolence; bradycardia, arrhythmias, tachycardia. In case of any side effect, including those not listed in this instruction, consult your doctor or pharmacist. Overdose: In case of overdose symptoms, symptomatic treatment is required. Special instructions: TREVITON B is administered intramuscularly, not intravenously. In case of accidental intravenous administration, medical supervision is necessary. Use of this preparation for more than 6 months can lead to the development of neuropathy. This preparation contains 20mg/ml of benzyl alcohol. Benzyl alcohol can cause allergic reactions. If the patient is pregnant or breastfeeding, medical consultation is necessary. High amounts of benzyl alcohol can exacerbate or cause side effects (e.g., "metabolic acidosis"). Caution is advised when using high doses, and it is permitted only when necessary, especially in cases of liver or kidney failure due to the risk of accumulation and toxicity (metabolic acidosis). TREVITON B contains less than 1mmol of sodium (23mg) per dose (2ml). TREVITON B contains less than 1mmol of potassium (39mg) per dose (2ml), meaning it is "potassium-free". Pregnancy and lactation: Pregnancy: There is insufficient data on the effect of this preparation on pregnancy, fetus, prenatal, and postnatal development. The potential risk to humans is unknown. The recommended daily allowance (RDA) for thiamine (vitamin B1) during pregnancy is 1.4mg/day. The recommended daily allowance (RDA) for pyridoxine (vitamin B6) is 1.9mg/day; for women aged 18 years and younger during pregnancy and lactation, the maximum dose is 80mg/day, and for women over 18 years of age, it is 100mg/day.