Properties
What is it?
International Nonproprietary Name - DICLOFENAC SODIUM Clinical-Pharmacological Group: Non-steroidal anti-inflammatory drug. Indications: Inflammatory and degenerative rheumatic diseases: Rheumatoid arthritis; Juvenile rheumatoid arthritis (only 25 mg enteric-coated tablets and 25 mg rectal suppositories); Ankylosing spondylitis; Osteoarthritis; Spondyloarthritis; Spinal pain; Non-articular soft tissue rheumatic disease; Acute gout attack (only enteric-coated tablets); Post-traumatic and postoperative periods, accompanied by inflammation and swelling; Gynecological diseases, accompanied by primary dysmenorrhea and adnexitis. As an adjunct, Voltaren is used for inflammatory diseases of the ear, nose, and throat accompanied by pain, such as pharyngitis, tonsillitis, otitis (except for retard tablets). Dosage and Administration: For adults, the recommended initial dose is 100-150 mg/day, especially for mild forms of the disease. For long-term treatment, the daily dose is 75-100 mg. The daily dose should be divided into several administrations. Additionally, Voltaren suppositories can be used before bedtime, but the daily dose should not exceed 150 mg. For primary dysmenorrhea, the daily dose is determined individually and is 50-150 mg. The initial dose should be 50-100 mg; if necessary, the dose can be increased to 150 mg/day for several menstrual cycles. Treatment can be initiated at the first sign of symptoms. Treatment duration can be extended for several days depending on the clinical effect. For children aged 6 to 15 years, only 25 mg tablets are used. The daily dose is 0.5-2 mg/kg of body weight (2-3 times depending on the severity of the disease). For the treatment of rheumatoid arthritis, the daily dose can be increased to a maximum of 3 mg/kg (in several doses). For adolescents aged 16 to 18 years, 50 mg of the drug can be used. Tablets should be swallowed whole with liquid, preferably before meals. Side Effects: Gastrointestinal tract: Rarely, epigastric pain, nausea, vomiting, diarrhea, abdominal cramps, dyspepsia, abdominal bloating, anorexia; rarely - gastrointestinal bleeding (hematemesis, melena, diarrhea), peptic ulcer disease of the stomach and duodenum with bleeding and perforation; in isolated cases - aphthous stomatitis, glossitis; digestive changes, development of diaphragm-like strictures in the intestine, lower intestinal disorders, such as: exacerbation of nonspecific ulcerative colitis or Crohn's disease, constipation, pancreatitis.