Properties
What is it?
Composition: 1 tab. contains 20mg or 40mg famotidine. 1 vial contains 20mg famotidine lyophilized powder. Solvent: 5ml of 0.9% sodium chloride solution. Form: Film-coated tablets 20mg and 40mg. 20mg lyophilized powder for solution for injection. Pharmacotherapeutic group: Histamine H2 receptor blocker. Indication: Gastric and duodenal ulcer disease, erosive esophagitis caused by increased gastric secretory function, gastroesophageal reflux, reflux esophagitis, Zollinger-Ellison syndrome; prophylaxis of gastric recurrences; prophylaxis of gastric juice aspiration during general anesthesia (Mendelson's syndrome). Contraindication: Hypersensitivity to famotidine and other histamine H2 receptor blockers; pregnancy and lactation. In children. Dosage and administration: Film-coated tablets: For gastric and duodenal ulcers, usually 20mg twice daily or 40mg once daily before bedtime. The course of treatment mainly lasts for 4-8 weeks. Prophylaxis of ulcer recurrence - 20mg once daily before bedtime. Gastroesophageal reflux - 20mg twice daily in the morning and evening for 6 weeks, for esophagitis - 20-40mg twice daily for 12 weeks. Zollinger-Ellison syndrome: The dose of the preparation is individual and depends on the patient's condition. The initial dose is usually 20mg every 6 hours. The preparation is taken for a clinically established period. Prophylaxis of gastric juice aspiration during general anesthesia - 40mg in the evening before surgery, and then in the morning before surgery. Injections: Used only in severe cases, or when tablets cannot be taken. As an intravenous injection, the usual dose of the preparation is 20mg twice daily (every 12 hours). Zollinger-Ellison syndrome: The initial dose is 20mg intravenously, every 6 hours. Subsequently, the dose of the preparation depends on hydrochloric acid secretion and the patient's clinical condition. Prophylaxis of gastric juice aspiration during general anesthesia - 20mg of the preparation is administered intravenously before the start of general anesthesia on the day of surgery or at least 2 hours before the start of surgery. The single intravenous dose should not exceed 20mg. Before starting intravenous infusion, the powder in the vial should be dissolved in 5-10ml of 0.9% sodium chloride solution and the preparation should be injected slowly over 2 minutes. For intravenous infusion, the contents of the vial should be dissolved in 100ml of 5% glucose infusion solution. Intravenous infusion is carried out over 15-30 minutes. The solution of the preparation is prepared immediately before its use. Only a clear and transparent solution of the preparation is suitable for use. The opened injection solution is stored at a temperature of 25°C for no more than 24 hours. In case of renal failure with creatinine clearance less than 30ml/min, it is necessary to reduce the daily dose of the preparation (both for oral administration and intravenous injection) to 20mg, or to increase the interval between individual doses of the preparation to 36-48 hours. Dispensing rule - by doctor's prescription
