Properties
What is it?
1. What is Brenax and what is it used for Each ampoule of Brenax contains Citicoline Sodium, equivalent to 500 mg Citicoline or 1000 mg Citicoline. The cardboard box contains 5 ampoules. Brenax is prescribed for the treatment of the following conditions: • Acute phase of stroke caused by vascular occlusion; • Post-stroke period caused by vascular occlusion and hemorrhage; • During acute or subsequent treatment of traumatic brain injury; • Cognitive disorders caused by vascular and tissue damage. Special indications: Mannitol and corticosteroid preparations are essential for treating brain injury to reduce intracranial pressure. In case of intracranial hemorrhage, the single dose of citicoline should not exceed 500 mg. In this case, the dose should be divided (100-200 mg 2-3 times a day). 2. What you need to know before taking Brenax Do not take Brenax if: • You are hypersensitive to any component of the preparation; • You have vagotonia (neurotic nervous system, irregular heartbeat, constipation, sweating); • You are pregnant or breastfeeding, as there is no relevant clinical data; • Do not take Brenax with alcohol. In the above cases, do not take Brenax and consult your doctor, who will decide on the advisability of prescribing or using the medication for you. Special precautions are needed when taking Brenax if: • You are a geriatric (elderly) patient; • You are a driver or operate machinery. Consult your doctor for advice on whether the preparation is advisable for you. Taking Brenax with food and drink Depending on the route of administration, food and drink do not affect its absorption. Pregnancy Before taking the medication, consult your doctor or pharmacist. The preparation can be prescribed during pregnancy only if the therapeutic effect significantly outweighs the probability of risk to the fetus. Breastfeeding Before taking the medication, consult your doctor or pharmacist. If the preparation must be taken during breastfeeding, breastfeeding should be discontinued. Ability to drive and operate machinery During treatment, the patient should be very careful when driving a car or operating other machinery, as quick psychomotor reactions are necessary. Important information about the excipients of Brenax Each dose of Brenax contains less than 1 mmol of sodium (23 mg), so it is considered sodium-free. Drug interactions - Citicoline enhances the effect of Levodopa - This preparation should not be taken with preparations containing meclofenoxate - Brenax can be prescribed with hemostatic and intracranial antihypertensive agents and infusion solutions. Consult your doctor or pharmacist if you are taking or have recently taken any medication, including over-the-counter medicines. 3. How to take Brenax Dosage / frequency of administration The doctor will determine the appropriate dose of Brenax. Usually, 1 ampoule of Brenax is prescribed intramuscularly and intravenously (slow injection) every 12 hours. Method of use and route of administration Brenax is administered intramuscularly or intravenously. After breaking the ampoule, the contents drawn into a syringe are injected deep into the muscles using a sufficiently long needle. Before injecting the solution, the plunger should be slightly pulled back to ensure that no blood vessels have been damaged. The preparation can also be administered intravenously. Different age groups: Use in children and adolescents The efficacy and safety of Brenax in children and adolescents under 18 years of age have not been studied. Use in the elderly There is no relevant data on the efficacy and safety of Brenax in geriatric patients. Special circumstances: Pregnancy The preparation can be prescribed during pregnancy only if the therapeutic effect significantly outweighs the probability of risk to the fetus. If you think that the effect of Brenax is too strong or too weak, consult your doctor or pharmacist. Brenax overdose: In case of Brenax overdose, consult your doctor or pharmacist. Missed Brenax dose: Do not take a double dose of the medication to make up for a missed dose. Discontinuation of Brenax treatment: No side effects are expected after discontinuation of treatment. 4. Possible side effects Like all medicines, Brenax may cause side effects in individuals sensitive to its components. If any of the following side effects occur, stop taking Brenax and seek immediate medical attention at the nearest hospital emergency department. Central nervous system, peripheral nervous system: Insomnia, headache, irritability, agitation, tremor, stiffness of paralyzed limbs. Gastrointestinal tract: Stomach pain, decreased appetite, changes in liver enzyme activity. Allergic reactions: Rash, itching, anaphylactic shock. (Swelling of the face, tongue, throat, skin rash, shortness of breath, difficulty breathing, fever, or allergic reactions caused by shock). Other: Fever, in some cases - short-term hypotensive effect (lowering of blood pressure), stimulation of the parasympathetic nervous system (heart rhythm disturbances, conditions that may be associated with constipation and sweating). If side effects occur that are described in this instruction for use, consult your doctor or pharmacist immediately. These serious side effects are rare. Inform your doctor if you notice: Swelling of the face, tongue, throat, skin rash, shortness of breath, difficulty breathing, fever, or allergic reactions caused by shock. These are moderate side effects. If side effects occur that are not described in this instruction for use, consult your doctor or pharmacist immediately. 5. Storage conditions for Brenax Brenax should be stored out of reach of children, in its original packaging. Store at a temperature not exceeding 25˚C. Dispensing method: Pharmaceutical product group II, dispensed with prescription form #3. Use considering the expiry date: Do not use Brenax after the expiry date indicated on the box. Do not use Brenax if you notice that the preparation or its packaging is damaged.
