Properties
What is it?
General Characteristics: Basic physicochemical properties: Glycerin (1,2,3-propanetriol) or glycerol is a colorless, viscous (syrup-like), sweet-tasting, hygroscopic liquid. It is a substance for the preparation of ointments, liniments, suppositories, vaginal suppositories, and other medicinal forms. Dosage Form: Liquid Pharmacological Properties: Glycerin is constantly produced in the body during the enzymatic breakdown of fats. Both endogenous and exogenous glycerin undergo oxidation to carbonic acid and water. In pure form, glycerin (glycerol) has an irritating effect, which disappears when water (up to 30-50%), petrolatum, or lanolin is added. Glycerin reduces the irritating effect of many medicinal agents. It is almost not absorbed by the skin, but well absorbed by mucous membranes. Indications: The preparation is indicated as a softening agent for skin and mucous membranes, and also for constipation. Dosage and Administration: In adults, for dry, cracked skin, glycerin is administered as an application. As a laxative, in the form of suppositories and enemas (2-5ml). Side Effects: In case of overdose of the preparation, including a condition with increased absorption into the blood, it causes hemolysis, hemoglobinuria, and methhemoglobinic infarction of the kidneys. Intestinal irritation is possible. Contraindications: Inflammatory diseases and tumors of the gastrointestinal tract, increased uterine contractions, destructive skin processes. Shelf Life and Storage Conditions: The preparation should be stored in a dry, cool place, protected from children, in a tightly closed container. Expiration date is indicated on the packaging. Dosage Form: 25ml liquid in a vial
