Furosemide Tablet 40mg #20

Form

tableti

Dosage mg

40

Pack

20

International Nonproprietary Name - Furosemidum Pharmacological Group: Potent Diuretics Active Substance: Furosemide; 1 tablet contains 40 mg of Furosemide; Excipients: Corn Starch Modified, Microcrystalline Cellulose, Magnesium Stearate, Povidone, Macrogol 6000, Lactose Monohydrate. Pharmacotherapeutic Group. Diuretic. Methods of Use and Doses. Furosemide is administered orally before meals. The dose is selected based on the severity of the disease and the expressed effect. Administer 40 mg (1 tablet) orally once a day in the morning. If the effect is insufficient, increase the dose to 80 – 160 mg per day (2-3 times with 6-hour intervals). When reducing edema, prescribe in smaller doses with 1-2 day intervals. The maximum dose is 160 mg. For arterial hypertension, the initial dose in adults is 80 mg per day, divided into two doses. It should correspond to the patient's condition; if the effect is inadequate, it is necessary to prescribe it in combination with other hypotensive agents. In case of concomitant heart failure, the daily dose can be increased up to 80 mg. For children aged 3 years and above, the average daily dose, taken orally before or after meals, is 4 mg/kg, 1-4 times a day. The strongest diuretic effect is observed within the first 3-5 days. After edema disappears, switch to intermittent administration of Furosemide – every other day or 1-2 times a week. If the child has not previously taken Furosemide or other diuretics, it is not necessary to prescribe a diuretic at the average daily dose. Initially, it is necessary to use a diuretic dose that constitutes 1/3 of the average daily dose, and then, if the diuretic effect is insufficient, the dose should be increased. The initial dose for children is 2 mg/kg, and if necessary, it can be increased by 1-2 mg/kg. Symptoms of Overdose: Dehydration, reduced circulating blood volume, arterial hypotension, electrolyte imbalance, hypokalemia, and hypochloremic alkalosis, caused by the diuretic effect. In case of developing symptoms of overdose, the patient should immediately consult a doctor. Side Effects. Nausea, vomiting, hypovolemia, dehydration, hyperemia, skin itching, hypotension, cardiac rhythm disturbances, reversible hearing and vision impairments, paresthesias, interstitial nephritis are possible. Due to increased diuresis, dizziness, depression may develop; muscle weakness, thirst, dehydration, hypokalemia, hyponatremia, hypochloremia, metabolic alkalosis; transient hyperuricemia, uricosuria, exacerbation of gout, in isolated cases hyperglycemia, worsening of the condition in obstructive uropathy. Contraindications. Acute glomerulonephritis, end-stage renal failure, mechanical obstruction of the urinary tract, renal failure, diabetic coma; water-salt metabolism disorder (hypokalemia, hyponatremia, dehydration, alkalosis); first half of pregnancy, hypersensitivity to the drug (including sulfonamides), anuria, gout, decompensated arterial or mitral stenosis; pronounced hypotension, pancreatitis, myocardial infarction, diabetes mellitus with impaired carbohydrate tolerance, hypertrophic cardiomyopathy with obstruction of the left ventricular outflow tract, systemic lupus erythematosus. Age up to 3 years.